OADES, R. D., The Role of Norepinephrine and Serotonin in ADHD.
In:"“Attention Deficit Hyperactivity Disorder: From Genes to Animal Models to Patients”, D. Gozal and D. L. Molfese (Eds.), 2005 Humana Press, Totawa, NJ: pp 97-130. Request a copy View Chapter

CONTENTS:
1. Introduction ................................................................................................ 1
2. Biochemistry ............................................................................................... 2
3. CNS Pathways ........................................................................................... 3
....3.1 NE
....3.2 5-HT
4. Interactions between monoamines ................................................................ 5
....4.1 5-HT – NE
....4.2 5-HT – DA
....4.3 NE – DA
5. Development ............................................................................................... 7
....5.1 NE
....5.2 5-HT
6. Evidence for monoamine contributions to ADHD -- Genetic studies .............. 8
....6.1 NE
....6.2 5-HT
7. Methods ................................................................................................... 10
8. Animal Models .......................................................................................... 12
....8.1 Rodent ................................................................................................ 12
....8.2 Primate ................................................................................................ 14
9. Evidence for monoamine contributions to ADHD -- NE and 5-HT activity ...14
....9.1 Evidence from group comparisons ........................................................ 16
....9.2 Evidence from pharmacological treatments ............................................ 18
10. General .................................................................................................... 23

Fig. 1 : On the Noradrenergic Locus Coeruleus and Projections, below : Fig. 2 : Further below : the Serotonin System and Projections


Fig. 2 (right)