OADES,
R. D., The
Role of Norepinephrine and Serotonin in ADHD.
In:"“Attention Deficit Hyperactivity
Disorder: From Genes to Animal Models to Patients”, D.
Gozal and D. L. Molfese (Eds.), 2005 Humana Press, Totawa, NJ:
pp 97-130. Request a
copy View
Chapter
CONTENTS:
1. Introduction ................................................................................................
1
2. Biochemistry ...............................................................................................
2
3. CNS Pathways ...........................................................................................
3
....3.1 NE
....3.2 5-HT
4. Interactions between monoamines ................................................................
5
....4.1 5-HT – NE
....4.2 5-HT – DA
....4.3 NE – DA
5. Development ...............................................................................................
7
....5.1 NE
....5.2 5-HT
6. Evidence for monoamine contributions
to ADHD -- Genetic studies .............. 8
....6.1 NE
....6.2 5-HT
7. Methods ...................................................................................................
10
8. Animal Models ..........................................................................................
12
....8.1 Rodent ................................................................................................
12
....8.2 Primate ................................................................................................
14
9. Evidence for monoamine contributions
to ADHD -- NE and 5-HT activity ...14
....9.1 Evidence from group comparisons
........................................................ 16
....9.2 Evidence from pharmacological
treatments ............................................ 18
10. General ....................................................................................................
23
Fig. 1 : On the Noradrenergic
Locus Coeruleus and Projections, below : Fig. 2 : Further
below : the Serotonin System and Projections
Fig.
2 (right)
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