OADES, R.
D. (1998). Frontal, temporal and lateralized brain function in
children with attention-deficit hyperactivity-disorder: a psychophysiological
and neuropsychological viewpoint on development. Behavioural Brain
Research, 94, 83-95. (request
a copy)
In accord with our understanding of journal policy,
we present the pre-publication
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The final version (cited above: doi:10.1016/S0166-4328(97)00172-1
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Introduction:
This review considers deficits in the selective aspects of perception
(i.e. attention) underlying symptoms of impaired attention and impulsivity
in children with attention-deficit hyperactivity syndrome (ADHD) in
terms of frontal and temporal lobe function and cerebral asymmetry.
Review:
Tomographic studies suggest a disturbance of fronto-striatal function,
but have neglected limbic contributions under activating conditions
and are contradictory or equivocal on the nature of apparent lateralised
differences of structure.
Functional neuropsychological (e.g. go/no-go and covert orienting of
attention tasks) and psychophysiological studies (e.g. event-related
potentials and mismatch negativity [1])
suggest that early and late stages of information processing are affected
in both the frontal and temporal lobes.
Performance differences in young ADHD patients imply an impairment in
the inter-cortical dialogue. Given the evidence for a normal specialisation
in global processing in the right and the processing of details in the
left hemisphere, the lateralised impairment may progress from
situational ADHD (resulting in impaired selective aspects of perception
on the right) to pervasive ADHD (inducing an additional impairment in
decision making on the left: compare risk taking).
Conclusions:
Accordingly a proportion of ADHD children may experience an early
negative neurodevelopmental influence that only appears as the brain
region matures (especially around 8-12 years of age) while others
show an independent, longer term, delayed development of CNS function.
[1] Oades
et al. 1996
see also Oades
1989 and Oades
1987
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